| An LC-MS/MS screening assay to monitor 88 pesticides using minimal LC separation was developed using the TSQ Quantum Discovery. It was possible to detect all components within a chromatographic timescale of 16 minutes by performing 88 SRM transitions. Even with dwell times of only 20 milliseconds, no cross-talk interfered with the analysis.
The absence of cross-talk was demonstrated by extracting and comparing the ion chromatograms of similar classes of compounds with different precursor ion masses but with the same product ion mass.
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