Power of MSn Combined with the
Speed of MALDI
The Thermo Scientific MALDI LTQ Orbitrap combines the benefits of
MALDI technique with Orbitrap technology. The addition of the new MALDI source
to the LTQ Orbitrap is ideally suited for proteomics and metabolism
applications.
The MALDI LTQ Orbitrap provides fast, reliable, confident and
complementary protein identification and enables for various analytical
approaches to localize post-translational modifications. Outstanding mass
accuracy and high sensitivity make the MALDI LTQ Orbitrap a superior
alternative to traditional MALDI-TOF systems.
The MALDI source makes it easier to analyze a large variety of
biological and polymer samples with fast sample preparation. The MALDI LTQ
Orbitrap supports a wide range of applications as MALDI provides valuable
information in state-of-the-art analyses.
 | The MALDI option is available for
both the LTQ Orbitrap Discovery and
the LTQ Orbitrap XL. |
The MALDI LTQ Orbitrap
offers:
- High throughput analysis of in-gel digests of
2D gel spots for protein ID
- CID, PQD, and HCD fragmentation technique for
complementary peptide information
- de novo sequencing, iTRAQ™
quantitation, tissue imaging and small molecule analysis
- Resolutions of greater than 50,000 FWHM and
mass accuracies of 2 ppm routinely available for MS, MS/MS and MSn
data.
| MALDI technique combined with
Orbitrap technology |
| MALDI Technique | Orbitrap
Technology |
- Robust laser optics
- Direct beam
- Nitrogen laser
- Crystal Positioning System (CPS)
- Tissue Imaging enabled
|
- Routine FT mass accuracy
- Superior resolving power
- > 100,000 resolution
- Wide dynamic range
- Parallel MS and MSn analysis
- Multiple dissociation techniques: CID, PQD, and HCD
|
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