MicroRNAs (miRNAs) are a growing class of small, noncoding RNAs (17-25nt) that regulate gene expression by targeting mRNAs for translational repression, degradation, or both. To advance research on the function and mechanisms of these molecules, we offer Thermo Scientific Dharmacon miRIDIAN microRNA research products.
Product Detail
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miRIDIAN microRNA Mimics
• Synthetic miRNA mimics designed to enter miRNA pathway and act as mature miRNA species
• Supplement native miRNA activity to further decrease steady-state protein levels and study gain-of-function effects
miRIDIAN microRNA Inhibitors
• Synthetic miRNA inhibitors designed to specifically target and irreversibly bind endogenous miRNAs
• Suppress native miRNA activity to increase protein levels and study loss-of-function effects
miRIDIAN microRNA Mimic and Inhibitor Negative Controls
• Mimic and Inhibitor molecules based on C. elegans miRNAs with no known homologs in human, mouse, or rat
• For use as non-targeting negative controls in Inhibitor and Mimic experimentation
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