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The new MALDI LTQ Orbitrap series simplifies the analysis of
whole tissue, biological and polymer samples by eliminating sample preparation.
The new MALDI source, available on the LTQ Orbitrap XL and
Discovery, is ideally suited for proteomics and metabolism applications.
Resolution of greater than 50,000 FWHM and mass accuracies of 2 ppm are
available for MS, MS/MS and even MSn data.
Using the high
resolving power and outstanding mass accuracy of the LTQ Orbitrap, researchers
can now perform peptide and protein identification of MALDI-produced ions.
Other important applications include the high-throughput analysis of in-gel
digests of 2D gel spots, de novo sequencing, iTRAQ™ quantitation, tissue
imaging and small molecule analysis.
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The LTQ Orbitrap XL ETD is the only ETD instrument with both
high resolution and accurate mass, enabling definitive protein
characterization.
Thermo Scientific ETD technology enables highly sensitive
post-translational modification analyses. Combined with the LTQ Orbitrap XL,
ETD completes the most advanced proteomics platform available by offering three
complementary fragmentation techniques in one instrument:
CID, HCD and ETD
for definitive protein/peptide characterization, post-translational
modification (PTM) analysis (especially phosphorylation); and top-down or
middle-down sequencing of proteins and peptides.
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